Deborah E. Powell

Center for Women's Health

A National Center of Excellence

Seed Grant Awardees

Congratulations to our 2013-2014 Women's Health Interdisciplinary Seed Grant awardees!

In 2013, as part of the Powell Center’s strategic plan to increase the number of researchers focusing on women’s health, an RFA was issued for funding for 2 seed grants of $25,000 each. The goal of the seed money was to provide starter funds for interdisciplinary research projects that would provide a basis for and enable faculty to apply for an R01 NIH grant. We received 8 applications. In February 2013, grant applications were reviewed by senior faculty associated with the Powell Center and two awardees were chosen.

 

AHCWMHLTH2 - Image - 180x222 - Seed Grant - AA         AHCWMHLTH2 - Image - 180x222 - Seed Grant - EL
Alicia Allen, PhD, MPH Emil Lou, MD, PhD

 

Alicia Allen, PhD, MPH
Assistant Professor in the Department of Family Medicine and Community Health
Medical School

Mentors:

  • Sharon Allen, MD, PhD, Professor, Department of Family Medicine & Community Health, University of Minnesota Medical School
  • Lynn Eberly, PhD, Associate Professor, Division of Biostatistics, University of Minnesota School of Public Health
  • Mustafa al'Absi, PhD, Department of Behavioral Sciences, University of Minnesota Medical School Duluth
  • Marilyn Carroll, PhD, Professor, Department of Psychiatry, University of Minnesota Medical School
  • John Grabowski, PhD, Professor, Department of Psychiatry, University of Minnesota Medical School
  • Sheila Specker, MD, Professor, Department of Psychiatry, University of Minnesota Medical School

Research Title: Allopregnanolone in Smoking and Cocaine Cessation

Her research project will collect preliminary evidence for the possible role of allopregnanolone (ALLO) in the cessation of drug abuse. ALLO is a stress-reducing neuroactive steroid metabolized from the sex hormone progesterone. Dr. Allen states, “Preclinical research indicates ALLO has protective effects against the drug abuse behaviors of escalation, reinstatement, and withdrawal; some of these associations varied by sex.” Dr. Allen hypothesizes that there will be an inverse association between ALLO and cessation-related symptomatology (CRS) such that higher ALLO levels will be associated with less severe CRS and the association between ALLO and CRS will be stronger in women than in men.

Dr. Allen’s interdisciplinary team consists of Dr. Sharon Allen, Professor in the Department of Family Medicine and Community Health, Dr. Lynn Eberly, Associate Professor in the Division of Biostatistics in the School of Public Health, Dr. Mustafa al’Absi, Department of Behavioral Sciences at the University of Minnesota, Duluth, Dr. John Grabowski, Department of Psychiatry, and Dr. Sheila Specker, Department of Psychiatry.

 

Emil Lou, MD, PhD
Assistant Professor in the Division of Hematology, Oncology and Transplantation
Department of Medicine, Medical School

Mentors:

  • Subbaya Subramanian, PhD, Assistant Professor, Department of Surgery, University of Minnesota Medical School
  • Melissa Geller, MD, Assistant Professor, Division of Gynecologic Oncology, Department of OB/GYN & Women's Health, University of Minnesota Medical School
  • Elizabeth Dickson, MD, Clinical Fellow, Gynecologic Oncology
  • Venugopal Thayanithy, PhD, Research Associate/Postdoctoral Fellow
  • Rachel Vogel Isaksson, MS, Biostatistics and Bioinformatics Core, Masonic Cancer Center
  • Clifford J. Steer, MD, Division of Hepatology, Department of Medicine, University of Minnesota Medical School
  • Richard King, MD, PhD, Professor, Department of Medicine, University of Minnesota Medical School

Research Title: Role of Intercellular Communication via Tunneling Nanotubes in Developing Chemoresistant Ovarian Cancer

Dr. Lou will investigate tunneling nanotubes (TnTs) as a previously unrecognized form of cell-to-cell communication in recurrent ovarian tumors and will assess these unique structures as potentially novel targets for effective therapy. Dr. Lou hypothesizes that understanding mechanisms and properties of TnTs in the context of the heterogeneous tumor microenvironment will lead to identification of novel target for delaying ovarian cancer recurrence and understanding development of chemotherapy resistance.

Dr. Emil’s interdisciplinary team consists of Dr. Subbaya Subramanian, Department of Surgery, Dr. Melissa Geller, Department of OB/GYN, Division of Gynecologic Oncology, Dr. Elizabeth Dickson, Clinical Fellow, Gynecologic Oncology, Dr. Venugopal Thayanithy, Research Associate/Postdoctoral Fellow, Dr. Rachel Vogel Isaksson, Biostatistics and Bioinformatics Core, Masonic Cancer Center, Dr. Clifford J. Steer, Department of Medicine, Division of Hepatology, and Dr. Richard King, Department of Medicine.
 

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  • Last modified on May 22, 2013